Preimplantation Genetic Testing for Aneuploidy (PGT-A) is a genetic test performed on embryos during IVF treatment to screen for numerical chromosomal abnormalities (aneuploidies), such as extra or missing chromosomes.
PGT-A is conducted on an embryo biopsy prior to transfer and helps identify which embryos have a normal chromosome number. Chromosomally normal (euploid) embryos have a higher likelihood of developing to term and resulting in a healthy baby.
PGT-A assists IVF physicians and patients in selecting the best embryos for transfer, improving the chances of a successful pregnancy and reducing the risk of miscarriage.
Preimplantation Genetic Testing for Monogenic Disorders (PGT-M) is a genetic test performed during IVF when one or both parents carry a known single-gene mutation. It helps determine whether an embryo has inherited the specific genetic disorder.
PGT-M is conducted on a small embryo biopsy before implantation to identify which embryos are free of the disease-causing mutation. This allows for the selection of embryos with a lower risk of developing the condition.
The goal of PGT-M is to help couples build a healthy family by reducing the risk of passing on inherited genetic disorders. Since testing is done before pregnancy is established, it helps avoid difficult reproductive decisions later on.